MTHFR, Methylation, and Grass-Fed Liver

Methylation is an incredibly important process in the human body. These methylation processes occur many times each second, in every cell in the human body. Methylation is a necessary process for human beings to thrive!

These processes require many nutrients and vitamins to occur. Most notably, many of the B vitamins (B2, B3, Pantothenic Acid B5, Pyridoxine B6, Folate B9, B12), zinc, choline, betaine, and taurine are all necessary for adequate methylation.

The human genome has many polymorphisms that can impact one’s ability to methylate. In other words, my ability to methylate may be very different from the reader’s ability to methylate. These polymorphisms include MTHFR (the most notable and infamous of the polymorphisms), MTRR, CBS, COMT, and others.

In the case that one has one or more of these polymorphisms, it becomes even more important for that individual to supply adequate amounts of each nutrient required for the methylation process.

Fortunately and coincidentally, liver from grass-fed ruminant species (and especially bison!) is incredibly rich in ALL (yes, ALL) of the nutrients required for optimum methylation.

Adequate ability to methylate has an impact on:

• neurotransmitter regulation & biosynthesis (impacts mental states like anxiety, depression, etc.)

• immunoregulation (impacts ability to fight colds, viruses, allergies, etc.)

• genetic expression, DNA repair, and epigenetics (cell division, DNA&RNA synthesis, sense of youth and anti-aging)

• energy and metabolism (stamina, endurance, mental clarity)

• detoxification systems (toxin and histamine clearance)

• cardiovascular health (longevity and athletic performance)

• hormonal regulation (libido, muscle mass, energy)

In short, methylation has an effect on our day-to-day living. The ability to methylate properly can impact our everyday quality of life!

Some folks with methylation polymorphisms report dramatic changes in their daily quality of life once their methylation issues are adequately addressed.

It’s rare for a single food to offer so many of the nutrients that are so key to metabolic processes in the body, but grass-fed bison liver checks all the boxes for methylation. This may account for the rapid and profound impact that consuming liver and organ meats can have on one’s energy levels and subjective sense of clarity, mental energy, and stamina—if someone has never had the ability to properly methylate, and is then introduced to adequate nutrient levels for the processes to occur, then they can expect that everything is just going to work better!

This is often the case, and likely the reason why so many users of Paleo-Plex and 100% Grass-Fed Bison Liver & Organ Complex report immediate increases to their energy levels and feelings of well-being.

Key takeaways

• Methylation is a cellular process that impacts almost every system in the human body

• Adequate methylation abilities have an impact on our day-to-day living

• Anywhere from 10-40% of the general population has genetic polymorphisms impacting their ability to properly methylate

• Methylation can be dramatically improved by supplying adequate amounts of necessary nutrients and vitamins

• Grass-fed Bison Liver is rich in ALL of the nutrients necessary for methylation

• Eating Grass-fed Bison Liver can significantly improve one’s quality of life and ability to perform optimally!

related resources

1. https://calmerme.com/liver-key-source-of-methylation-nutrients/

2. https://wholisticmatters.com/food-nutrition-methylation/

3. https://www.armstrongsisters.com/post/eating-to-nurture-methylation-carnivore-nutrition-recommendations

4. https://www.aimc.edu/2019/11/04/balancing-methylation-through-diet-part-ii/

5. https://www.liverdoctor.com/methylation/